Center for Genomics and Systems Biology
Mission Statement: The mission of the Center for Genomics & Systems Biology is to define how regulatory networks operate and how they have evolved to generate diversity across species. For this work, we use approaches that span systems biology, comparative functional genomics & bioinformatic analysis focusing on model organisms and phylogenetically related species. The research involves the combined skills of genomicists, bioinformaticians, systematists, and evolutionary biologists all working together. The genomic & bioinformatic faculty in our center are engaged in collaborative projects with scientists at NYU's Courant Institute of Math & Computer Sciences, The American Museum of Natural History (AMNH), The New York Botanical Garden (NYBG), and Cold Spring Harbor Laboratories (CSHL), as well as collaborators at Harvard and Rockefeller University. The unique intellectual synergisms brought about by this collaborative genomic consortium group, enables us to develop unique approaches to address questions of comparative functional genomics.
Faculty Search Advertisement
click here to PDF link for advertisement
Genome Labs and Core Facilities: NYU Center for Genomics & Systems Biology: Endless Possibilities (.mov)
The Genome Center labs include four components: GENOMICS1. Genomic Laboratories 2. Genome Core Facility
BIOINFORMATICS Genomic Laboratories: The genome labs and core facilities in NYU's Center for Genomics & Systems Biology currently occupy 16,000 sq. ft in Brown Building (7th & 8th floors) with the entrance on 24-26 Waverly Place. Each floor of the genome center occupies approximately 8,000 Sq ft., which includes "open plan" laboratories with space for four PIs plus 47 researchers (wet bench plus bioinformatics), plus rooms for common equipment, and a genome core facility. This "open plan" laboratory space includes space for "wet-bench" genomic work and bioinformatics stations. The "open plan" genomics lab typifies the spirit of collaboration and interactions so exceptional within the Biology Department. Genome Core Facility: The Core Facility includes an Imaging Facility run by Dr. Ignatius Tan that currently includes state of the art microscopes including a Leica Spectral Confocal Microscope and Improvision Spinning Disk Confocal system for high through-put imaging. Both confocal systems have separate computer workstations configured to run Leica and Improvision’s Volocity image analysis software . The DNA Facility includes genome expression equipment including an Affymetrix GeneScan Hybridization and Reader system, Agilent 2100 Bioanalyzer, GenePix Personal 4100A microarray scanner from Axon Instruments, a Light Cycler, and several automated DNA sequencers. The Robotics Facility includes an Acquarius multi-channel pipettor with autoloader by Tecan and a Tecan EVO platform configured with shaking incubator, tilting, cooling and heating carriers, a vacuum system, multi-channel pipetting head, bar code reader, and the Infinite M200 microplate reader. As a stand-alone or part of the EVO platform, the Infinite M200 reader is fully loaded incubating, shaking reader with (top/bottom read) fluorescence, luminometer, and excitation and emission monochromator options. The Cellular & Phenotyping Facility consists of the BD FACS Aria a high speed cell sorter with two laser lines (488, 633 nm) capable of automated dispensing into a 96 well format and sterile environment. Bacterial samples can be sorted through a forward scattering PMT. Bioinformatics Suites and Cluster: The Bioinformatics suites in the Center for Genomics and Systems Biology contain approximately 30 workstations and associated computers. The computer cluster that serves these bioinformatics stations is presently comprised of 26 computational nodes, each with at least 4GB RAM. In addition to many essential software programs, the cluster uses the Sun Grid Engine for load balancing and process distribution among 34 Opteron 242 2.2 GHz processors. Disk storage available is currently over 10 terabytes. The Systems Administrator for the Bioinformatics cluster at NYU's Center for Genomics and Systems Biology is John Bako. To inquire about access, please send an e-mail to fas.bio.computing@nyu.eduNYU Super Computer ("MAX"): To further support the bioinformatics initiatives at NYU's Center for Genomics and Systems Biology, NYU has acquired a new IBM eServer Blade Center-based computing system capable of 4.5 TeraFlops; it is the fastest supercomputer in New York City and the 117th fastest in the world. With 10 TB of attached disk storage, this super computer cluster, named "MAX", provides an excellent platform for modeling biological systems and for manipulating the enormous amounts of data from genome sequencing and high-throughput microscopy, among other applications. Though the MAX cluster serves the entire university, researchers at NYU's Center for Genomics and Systems Biology receive priority access. Recent Publications News & Events |
|
|
|
Sitemap | Contact us | © New York University, Arts and Science 
|
